Cargando…
Impact of pseudouridylation, substrate fold, and degradosome organization on the endonuclease activity of RNase E
The conserved endoribonuclease RNase E dominates the dynamic landscape of RNA metabolism and underpins control mediated by small regulatory RNAs in diverse bacterial species. We explored the enzyme's hydrolytic mechanism, allosteric activation, and interplay with partner proteins in the multico...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522691/ https://www.ncbi.nlm.nih.gov/pubmed/34341070 http://dx.doi.org/10.1261/rna.078840.121 |