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Safe and easy in vitro evaluation of tmRNA-SmpB-mediated trans-translation from ESKAPE pathogenic bacteria

In bacteria, trans-translation is the major quality control system for rescuing stalled ribosomes. It is mediated by tmRNA, a hybrid RNA with properties of both a tRNA and a mRNA, and the small protein SmpB. Because trans-translation is absent in eukaryotes but necessary for bacterial fitness or sur...

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Detalles Bibliográficos
Autores principales:	Thépaut, Marion, Campos-Silva, Rodrigo, Renard, Eva, Barloy-Hubler, Frédérique, Ennifar, Eric, Boujard, Daniel, Gillet, Reynald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522692/ https://www.ncbi.nlm.nih.gov/pubmed/34353925 http://dx.doi.org/10.1261/rna.078773.121

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