Cargando…
Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017
OBJECTIVE: To analyze the evolution of syphilis during pregnancy notification regarding clinical classification, diagnosis and treatment in the state of Goiás, Brazil, between 2007 and 2017. METHODS: This is a time-series study, analyzing data provided by the Health Secretariat of the state of Goiás...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculdade de Saúde Pública da Universidade de São Paulo
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522754/ https://www.ncbi.nlm.nih.gov/pubmed/34730749 http://dx.doi.org/10.11606/s1518-8787.2021055003122 |
_version_ | 1784585152588939264 |
---|---|
author | de Oliveira, Iana Mundim Oliveira, Rívert Paulo Braga Alves, Rosane Ribeiro Figueiredo |
author_facet | de Oliveira, Iana Mundim Oliveira, Rívert Paulo Braga Alves, Rosane Ribeiro Figueiredo |
author_sort | de Oliveira, Iana Mundim |
collection | PubMed |
description | OBJECTIVE: To analyze the evolution of syphilis during pregnancy notification regarding clinical classification, diagnosis and treatment in the state of Goiás, Brazil, between 2007 and 2017. METHODS: This is a time-series study, analyzing data provided by the Health Secretariat of the state of Goiás. The variables related to the diagnosis and treatment of pregnant women and their partners were analyzed, and their evolution trend during the years. Descriptive statistics and percentage calculation were used. Cochran-Armitage test with a significance level α = 0.05 was used to determine increase and decrease trends. RESULTS: During the period, 7,774 cases were notified. The highest percentage of notifications occurred in the second trimester of pregnancy (39.8%) and corresponded to primary syphilis (34.1%). The most frequent treatment prescribed was benzathine benzylpenicillin with a dosage of 7.2 million (43.8%). Between 2007 and 2017, there was an increasing trend in the notification percentage of latent (14.1% to 30.7%), secondary (5.2% to 19%), and tertiary syphilis (4.4% to 11.4%). The treatment with benzathine benzylpenicillin with a dosage of 7.2 million also increased (19.3% to 59.6%). The percentages of primary syphilis decreased (43.4% to 22.1%), as well as other treatments’ percentages. CONCLUSIONS: Latent syphilis notification of pregnant women and treatment with penicillin at the dosage of 7,200,000 IU increased. Notification forms’ data completeness also increased for the variables clinical classification and treatment, suggesting improvements in the notification process. |
format | Online Article Text |
id | pubmed-8522754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Faculdade de Saúde Pública da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-85227542021-10-22 Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 de Oliveira, Iana Mundim Oliveira, Rívert Paulo Braga Alves, Rosane Ribeiro Figueiredo Rev Saude Publica Original Article OBJECTIVE: To analyze the evolution of syphilis during pregnancy notification regarding clinical classification, diagnosis and treatment in the state of Goiás, Brazil, between 2007 and 2017. METHODS: This is a time-series study, analyzing data provided by the Health Secretariat of the state of Goiás. The variables related to the diagnosis and treatment of pregnant women and their partners were analyzed, and their evolution trend during the years. Descriptive statistics and percentage calculation were used. Cochran-Armitage test with a significance level α = 0.05 was used to determine increase and decrease trends. RESULTS: During the period, 7,774 cases were notified. The highest percentage of notifications occurred in the second trimester of pregnancy (39.8%) and corresponded to primary syphilis (34.1%). The most frequent treatment prescribed was benzathine benzylpenicillin with a dosage of 7.2 million (43.8%). Between 2007 and 2017, there was an increasing trend in the notification percentage of latent (14.1% to 30.7%), secondary (5.2% to 19%), and tertiary syphilis (4.4% to 11.4%). The treatment with benzathine benzylpenicillin with a dosage of 7.2 million also increased (19.3% to 59.6%). The percentages of primary syphilis decreased (43.4% to 22.1%), as well as other treatments’ percentages. CONCLUSIONS: Latent syphilis notification of pregnant women and treatment with penicillin at the dosage of 7,200,000 IU increased. Notification forms’ data completeness also increased for the variables clinical classification and treatment, suggesting improvements in the notification process. Faculdade de Saúde Pública da Universidade de São Paulo 2021-10-18 /pmc/articles/PMC8522754/ /pubmed/34730749 http://dx.doi.org/10.11606/s1518-8787.2021055003122 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article de Oliveira, Iana Mundim Oliveira, Rívert Paulo Braga Alves, Rosane Ribeiro Figueiredo Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 |
title | Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 |
title_full | Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 |
title_fullStr | Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 |
title_full_unstemmed | Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 |
title_short | Diagnosis, treatment, and notification of syphilis during pregnancy in the state of Goiás, Brazil, between 2007 and 2017 |
title_sort | diagnosis, treatment, and notification of syphilis during pregnancy in the state of goiás, brazil, between 2007 and 2017 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522754/ https://www.ncbi.nlm.nih.gov/pubmed/34730749 http://dx.doi.org/10.11606/s1518-8787.2021055003122 |
work_keys_str_mv | AT deoliveiraianamundim diagnosistreatmentandnotificationofsyphilisduringpregnancyinthestateofgoiasbrazilbetween2007and2017 AT oliveirarivertpaulobraga diagnosistreatmentandnotificationofsyphilisduringpregnancyinthestateofgoiasbrazilbetween2007and2017 AT alvesrosaneribeirofigueiredo diagnosistreatmentandnotificationofsyphilisduringpregnancyinthestateofgoiasbrazilbetween2007and2017 |