Cargando…

A Novel Oxazolidinone, Contezolid (MRX-I), Expresses Anti-Mycobacterium abscessus Activity In Vitro

An evaluation of the anti-Mycobacterium abscessus activity expressed by a novel oxazolidinone, contezolid (MRX-I), toward 12 reference strains and 194 clinical isolates was conducted. Contezolid was active against M. abscessus in vitro, with effects comparable to the anti-M. abscessus effects of lin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Qi, Xu, Liyun, Tan, Fusheng, Zhang, Yongjie, Fan, Junsheng, Wang, Xinghai, Zhang, Zhemin, Li, Bing, Chu, Haiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Susceptibility
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522767/ https://www.ncbi.nlm.nih.gov/pubmed/34460305 http://dx.doi.org/10.1128/AAC.00889-21

Ejemplares similares

A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo
por: Wu, Wenye, et al.
Publicado: (2022)

Antibacterial activity of the novel oxazolidinone contezolid (MRX-I) against Mycobacterium abscessus
por: Gao, Shan., et al.
Publicado: (2023)

AR-12 Exhibits Direct and Host-Targeted Antibacterial Activity toward Mycobacterium abscessus
por: Zhang, Shaoyan, et al.
Publicado: (2020)

Determination of MIC Distribution and Mechanisms of Decreased Susceptibility to Bedaquiline among Clinical Isolates of Mycobacterium abscessus
por: Li, Bing, et al.
Publicado: (2018)

Vancomycin and Clarithromycin Show Synergy against Mycobacterium abscessus In Vitro
por: Mukherjee, Devika, et al.
Publicado: (2017)

Rifabutin Is Active against Mycobacterium abscessus Complex
por: Aziz, Dinah Binte, et al.
Publicado: (2017)

The in vitro effect of new combinations of carbapenem–β-lactamase inhibitors for Mycobacterium abscessus
por: Fröberg, Gabrielle, et al.
Publicado: (2023)

Mycobacterium abscessus Smooth and Rough Morphotypes Form Antimicrobial-Tolerant Biofilm Phenotypes but Are Killed by Acetic Acid
por: Clary, Gillian, et al.
Publicado: (2018)

In vitro activities of contezolid (MRX-I) against drug-sensitive and drug-resistant Mycobacterium tuberculosis
por: An, Huiru, et al.
Publicado: (2023)

Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates In Vitro and in a Mouse Model of Pulmonary Infection
por: Nicklas, Danielle A., et al.
Publicado: (2022)

MAB_2355c Confers Macrolide Resistance in Mycobacterium abscessus by Ribosome Protection
por: Guo, Qi, et al.
Publicado: (2021)

Sitafloxacin Expresses Potent Anti-Mycobacterium abscessus Activity
por: He, Siyuan, et al.
Publicado: (2022)

Molecular Analysis of Linezolid-Resistant Clinical Isolates of Mycobacterium abscessus
por: Ye, Meiping, et al.
Publicado: (2019)

In Vitro Profiling of Antitubercular Compounds by Rapid, Efficient, and Nondestructive Assays Using Autoluminescent Mycobacterium tuberculosis
por: Shetye, Gauri S., et al.
Publicado: (2021)

Clinical Efficacy and Adverse Effects of Antibiotics Used to Treat Mycobacterium abscessus Pulmonary Disease
por: Chen, Jianhui, et al.
Publicado: (2019)

Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients
por: Reichmuth, Martina L., et al.
Publicado: (2020)

Phenotypically Adapted Mycobacterium tuberculosis Populations from Sputum Are Tolerant to First-Line Drugs
por: Turapov, Obolbek, et al.
Publicado: (2016)

Developing Synergistic Drug Combinations To Restore Antibiotic Sensitivity in Drug-Resistant Mycobacterium tuberculosis
por: Omollo, Charles, et al.
Publicado: (2021)

Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis
por: Gold, Ben, et al.
Publicado: (2015)

Omadacycline, Eravacycline, and Tigecycline Express Anti-Mycobacterium abscessus Activity In Vitro
por: Li, Anqi, et al.
Publicado: (2023)

A Flow Cytometry Method for Rapidly Assessing Mycobacterium tuberculosis Responses to Antibiotics with Different Modes of Action
por: Hendon-Dunn, Charlotte Louise, et al.
Publicado: (2016)

Regrowth of Mycobacterium tuberculosis Populations Exposed to Antibiotic Combinations Is Due to the Presence of Isoniazid and Not Bacterial Growth Rate
por: Hendon-Dunn, Charlotte L., et al.
Publicado: (2019)

Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy
por: Li, Bing, et al.
Publicado: (2020)

Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh
por: Rahman, Arfatur, et al.
Publicado: (2017)

A Diagnostic Algorithm To Investigate Pyrazinamide and Ethambutol Resistance in Rifampin-Resistant Mycobacterium tuberculosis Isolates in a Low-Incidence Setting
por: Andres, Söenke, et al.
Publicado: (2019)

Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis
por: Rancoita, Paola M. V., et al.
Publicado: (2018)

Most-Probable-Number-Based Minimum Duration of Killing Assay for Determining the Spectrum of Rifampicin Susceptibility in Clinical Mycobacterium tuberculosis Isolates
por: Vijay, Srinivasan, et al.
Publicado: (2021)

Efflux Pumps Contribute to Intrinsic Clarithromycin Resistance in Clinical, Mycobacterium abscessus Isolates
por: Guo, Qi, et al.
Publicado: (2020)

Thin-Layer-Agar-Based Direct Phenotypic Drug Susceptibility Testing on Sputum in Eswatini Rapidly Detects Mycobacterium tuberculosis Growth and Rifampicin Resistance Otherwise Missed by WHO-Endorsed Diagnostic Tests
por: Ardizzoni, E., et al.
Publicado: (2021)

In Vitro Susceptibility and Resistance of Mycoplasma genitalium to Nitroimidazoles
por: Wood, Gwendolyn E., et al.
Publicado: (2023)

In Vitro and Intracellular Activities of Omadacycline against Legionella pneumophila
por: Dubois, Jacques, et al.
Publicado: (2020)

Decreased In Vitro Artemisinin Sensitivity of Plasmodium falciparum across India
por: Chakrabarti, Rimi, et al.
Publicado: (2019)

In Vitro Activity of Isavuconazole and Comparators against Clinical Isolates of the Mucorales Order
por: Arendrup, Maiken Cavling, et al.
Publicado: (2015)

In Vitro Activity of Solithromycin against Bordetella pertussis, an Emerging Respiratory Pathogen
por: Hardy, Dwight J., et al.
Publicado: (2016)

Synergistic Interactions of MmpL3 Inhibitors with Antitubercular Compounds In Vitro
por: Li, Wei, et al.
Publicado: (2017)

In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae
por: Miari, Victoria F., et al.
Publicado: (2017)

In Vitro Activity of Gepotidacin against Gram-Negative and Gram-Positive Anaerobes
por: Hackel, Meredith A., et al.
Publicado: (2022)

Antimicrobial Effect of Oxazolidinones and Its Synergistic Effect with Bedaquiline Against Mycobacterium abscessus Complex
por: Gao, Tianhui, et al.
Publicado: (2023)

In Vitro Activity of Meropenem-Vaborbactam against Clinical Isolates of KPC-Positive Enterobacteriaceae
por: Hackel, Meredith A., et al.
Publicado: (2017)

Development and Validation of an In Vitro Resazurin-Based Susceptibility Assay against Madurella mycetomatis
por: Abd Algaffar, S. O., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_aover5l6m3add9rogohv1lqvkq