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Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations

Body mass index (BMI) is a highly heritable polygenic trait. It is also affected by various environmental and behavioral risk factors. We used a BMI polygenic risk score (PRS) to study the interplay between the genetic and environmental factors defining BMI. First, we generated a BMI PRS that explai...

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Detalles Bibliográficos
Autores principales:	Borisevich, Dmitrii, Schnurr, Theresia M., Engelbrechtsen, Line, Rakitko, Alexander, Ängquist, Lars, Ilinsky, Valery, Aadahl, Mette, Grarup, Niels, Pedersen, Oluf, Sørensen, Thorkild I. A., Hansen, Torben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523041/ https://www.ncbi.nlm.nih.gov/pubmed/34662357 http://dx.doi.org/10.1371/journal.pone.0258748

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