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Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment

BACKGROUND: We previously observed that adenosine A1 receptor (A1AR) had a protective role in proximal tubular megalin loss associated with albuminuria in diabetic nephropathy (DN). In this study, we aimed to explore the role of A1AR in the fibrosis progression of DN. METHODS: We collected DN patien...

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Detalles Bibliográficos
Autores principales:	Tian, Dongli, Li, Jiaying, Zou, Linfeng, Lin, Min, Shi, Xiaoxiao, Hu, Yuting, Lang, Jiaxin, Xu, Lubin, Ye, Wenling, Li, Xuemei, Chen, Limeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523293/ https://www.ncbi.nlm.nih.gov/pubmed/34671682 http://dx.doi.org/10.1155/2021/5584871

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