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Adamantane-derived scaffolds targeting the sigma-2 receptor; an in vitro and in silico study
Novel adamantane-based compounds were synthesized and assessed as potential sigma-2 receptor ligands. Molecular docking and 50 ns molecular dynamic simulation were carried out to determine the binding modes, mechanism of interaction, and stability of these compounds within the active site of the sig...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523332/ https://www.ncbi.nlm.nih.gov/pubmed/34703370 http://dx.doi.org/10.1016/j.jsps.2021.08.016 |