A Case of Mal De Meleda: The Rare Presentation of Palmoplantar Keratoderma Disease

Mal de Meleda (MDM) is a rare sub-type of palmoplantar keratoderma (PPK) disease. The primary symptoms of PPK are scleroatrophy, transient keratoderma, scleroatrophic erythema, pseudoainhum around the digits, and perioral erythema. MDM is a pathology with a difficult clinical course. This case study...

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Detalles Bibliográficos
Autores principales: Kalyan, Vamsi, Suvvari, Tarun K, Kandula, Venkata Dinesh Kumar, Shanker, Aparajeya, Matiashova, Lolita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523366/
https://www.ncbi.nlm.nih.gov/pubmed/34692287
http://dx.doi.org/10.7759/cureus.18061
Descripción
Sumario:Mal de Meleda (MDM) is a rare sub-type of palmoplantar keratoderma (PPK) disease. The primary symptoms of PPK are scleroatrophy, transient keratoderma, scleroatrophic erythema, pseudoainhum around the digits, and perioral erythema. MDM is a pathology with a difficult clinical course. This case study presents two cases of MDM in siblings born out of second-degree consanguinity. The presenting complaint was the peeling of the palmar skin since birth. Both patients were treated with acitretin orally (dose: 10 mg) for three months and tretinoin (topical) for two months. The prognosis was good after three months of treatment.

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