Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors

Mitochondrial transcriptional factor A (TFAM) acts as a key regulatory to control mitochondrial DNA (mtDNA); the impact of TFAM and mtDNA in modulating carcinogenesis is controversial. Current study aims to define TFAM mediated regulations in head and neck cancer (HNC). Multifaceted analyses in HNC...

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Detalles Bibliográficos
Autores principales: Hsieh, Yi-Ta, Tu, Hsi-Feng, Yang, Muh-Hwa, Chen, Yi-Fen, Lan, Xiang-Yun, Huang, Chien-Ling, Chen, Hsin-Ming, Li, Wan-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523524/
https://www.ncbi.nlm.nih.gov/pubmed/34663785
http://dx.doi.org/10.1038/s41419-021-04255-w

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