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Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma

The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using single-cell RNA sequencing, we profile transcriptomes of 158,577 cells from 11 patients’ paratumors, localized/advanced tumors, initially-treated/recurrent lymph nodes and radioactive iodine (RAI)-refractory dist...

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Detalles Bibliográficos
Autores principales: Pu, Weilin, Shi, Xiao, Yu, Pengcheng, Zhang, Meiying, Liu, Zhiyan, Tan, Licheng, Han, Peizhen, Wang, Yu, Ji, Dongmei, Gan, Hualei, Wei, Wenjun, Lu, Zhongwu, Qu, Ning, Hu, Jiaqian, Hu, Xiaohua, Luo, Zaili, Li, Huajun, Ji, Qinghai, Wang, Jiucun, Zhang, Xiaoming, Wang, Yu-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523550/
https://www.ncbi.nlm.nih.gov/pubmed/34663816
http://dx.doi.org/10.1038/s41467-021-26343-3

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