Cargando…
Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma
The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using single-cell RNA sequencing, we profile transcriptomes of 158,577 cells from 11 patients’ paratumors, localized/advanced tumors, initially-treated/recurrent lymph nodes and radioactive iodine (RAI)-refractory dist...
Autores principales: | Pu, Weilin, Shi, Xiao, Yu, Pengcheng, Zhang, Meiying, Liu, Zhiyan, Tan, Licheng, Han, Peizhen, Wang, Yu, Ji, Dongmei, Gan, Hualei, Wei, Wenjun, Lu, Zhongwu, Qu, Ning, Hu, Jiaqian, Hu, Xiaohua, Luo, Zaili, Li, Huajun, Ji, Qinghai, Wang, Jiucun, Zhang, Xiaoming, Wang, Yu-Long |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523550/ https://www.ncbi.nlm.nih.gov/pubmed/34663816 http://dx.doi.org/10.1038/s41467-021-26343-3 |
Ejemplares similares
-
TERT accelerates BRAF mutant–induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis
por: Yu, Pengcheng, et al.
Publicado: (2023) -
Identification of Key Functional Gene Signatures Indicative of Dedifferentiation in Papillary Thyroid Cancer
por: Xu, Weibo, et al.
Publicado: (2021) -
A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer
por: Han, Litao, et al.
Publicado: (2021) -
Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway
por: Lu, KeBin, et al.
Publicado: (2020) -
Clinicopathological and Survival Outcomes of Well-Differentiated Thyroid Carcinoma Undergoing Dedifferentiation: A Retrospective Study from FUSCC
por: Ma, Ben, et al.
Publicado: (2018)