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Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway

G-protein-coupled receptors (GPCRs) are a target for over 34% of current drugs. The calcium-sensing receptor (CaSR), a family C GPCR, regulates systemic calcium (Ca(2+)) homeostasis that is critical for many physiological, calciotropical, and noncalciotropical outcomes in multiple organs. However, t...

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Detalles Bibliográficos
Autores principales: Gorkhali, Rakshya, Tian, Li, Dong, Bin, Bagchi, Pritha, Deng, Xiaonan, Pawar, Shrikant, Duong, Duc, Fang, Ning, Seyfried, Nicholas, Yang, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523568/
https://www.ncbi.nlm.nih.gov/pubmed/34663830
http://dx.doi.org/10.1038/s41598-021-00067-2