Cargando…

Mechanisms of Synaptic Transmission Dysregulation in the Prefrontal Cortex: Pathophysiological Implications

Prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the highest level cognitive and emotional processes. Its local circuits among glutamatergic principal neurons and GABAergic interneurons, as well as its long-range connections with other brain regions, have been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Zhen, Rein, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523584/ https://www.ncbi.nlm.nih.gov/pubmed/33875802 http://dx.doi.org/10.1038/s41380-021-01092-3

Ejemplares similares

Aβ impairs nicotinic regulation of inhibitory synaptic transmission and interneuron excitability in prefrontal cortex
por: Chen, Guo-Jun, et al.
Publicado: (2013)

Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology
por: Dwivedi, Y, et al.
Publicado: (2015)

Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex
por: Cai, Wei, et al.
Publicado: (2022)

Plasticity in Prefrontal Cortex Induced by Coordinated Synaptic Transmission Arising from Reuniens/Rhomboid Nuclei and Hippocampus
por: Banks, Paul J, et al.
Publicado: (2021)

Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain
por: Wruck, Wasco, et al.
Publicado: (2020)

Effects of TRPV1 Activation by Capsaicin and Endogenous N-Arachidonoyl Taurine on Synaptic Transmission in the Prefrontal Cortex
por: Zhang, Mingyue, et al.
Publicado: (2020)

5-HT-dependent synaptic plasticity of the prefrontal cortex in postnatal development
por: Higa, Guilherme Shigueto Vilar, et al.
Publicado: (2022)

Connectivity of Mouse Somatosensory and Prefrontal Cortex Examined with Trans-synaptic Tracing
por: DeNardo, Laura A., et al.
Publicado: (2015)

Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex
por: Sacai, Hiroaki, et al.
Publicado: (2020)

Muscarinic and Nicotinic Modulation of Thalamo-Prefrontal Cortex Synaptic Pasticity In Vivo
por: Bueno-Junior, Lezio Soares, et al.
Publicado: (2012)

Altered synaptic ultrastructure in the prefrontal cortex of Shank3-deficient rats
por: Jacot-Descombes, Sarah, et al.
Publicado: (2020)

Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex
por: Wu, Han-Fang, et al.
Publicado: (2015)

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
por: Narayanan, Manikandan, et al.
Publicado: (2014)

Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats
por: Pérez, Miguel Ángel, et al.
Publicado: (2019)

Treadmill Exercise Reduces Neuroinflammation, Glial Cell Activation and Improves Synaptic Transmission in the Prefrontal Cortex in 3 × Tg-AD Mice
por: Mu, Lianwei, et al.
Publicado: (2022)

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex
por: Schofield, Claude M, et al.
Publicado: (2011)

Multivariate synaptic and behavioral profiling reveals new developmental endophenotypes in the prefrontal cortex
por: Iafrati, Jillian, et al.
Publicado: (2016)

Dopaminergic Dysregulation in Prefrontal Cortex of Rhesus Monkeys Following Cocaine Self-Administration
por: McIntosh, Scot, et al.
Publicado: (2013)

Dysregulated Prefrontal Cortex Inhibition in Prepubescent and Adolescent Fragile X Mouse Model
por: Kramvis, Ioannis, et al.
Publicado: (2020)

Chronic Alcohol Exposure Alters Behavioral and Synaptic Plasticity of the Rodent Prefrontal Cortex
por: Kroener, Sven, et al.
Publicado: (2012)

Core Differences in Synaptic Signaling Between Primary Visual and Dorsolateral Prefrontal Cortex
por: Yang, Sheng-Tao, et al.
Publicado: (2018)

Differential Synaptic Dynamics and Circuit Connectivity of Hippocampal and Thalamic Inputs to the Prefrontal Cortex
por: Canetta, Sarah, et al.
Publicado: (2020)

Stress induces microglia-associated synaptic circuit alterations in the dorsomedial prefrontal cortex
por: Liu, Taohui, et al.
Publicado: (2021)

A Clinically-Relevant Dose of Methylphenidate Enhances Synaptic Inhibition in the Juvenile Rat Prefrontal Cortex
por: Urban, Kimberly R., et al.
Publicado: (2017)

Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder
por: Ribeiro, Efrain A., et al.
Publicado: (2017)

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia
por: Kindler, Jochen, et al.
Publicado: (2019)

Correction: Muscarinic and Nicotinic Modulation of Thalamo-Prefrontal Cortex Synaptic Plasticity In Vivo
por: Bueno-Junior, Lezio Soares, et al.
Publicado: (2012)

Stress and steroid regulation of synaptic transmission: from physiology to pathophysiology
por: Maggio, Nicola, et al.
Publicado: (2013)

Prefrontal cortex, amygdala, and threat processing: implications for PTSD
por: Alexandra Kredlow, M., et al.
Publicado: (2021)

Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice
por: Huo, XiaoJiao, et al.
Publicado: (2018)

Blocking Astrocytic GABA Restores Synaptic Plasticity in Prefrontal Cortex of Rat Model of Depression
por: Srivastava, Ipsit, et al.
Publicado: (2020)

Molecular pathology associated with altered synaptic transcriptome in the dorsolateral prefrontal cortex of depressed subjects
por: Yoshino, Yuta, et al.
Publicado: (2021)

S188. DYSREGULATION OF CIRCULAR RNA EXPRESSION IN SCHIZOPHRENIA OBSERVED IN POSTMORTEM DORSOLATERAL PREFRONTAL CORTEX
por: Mahmoudi, Ebrahim, et al.
Publicado: (2018)

Dopamine Modulates Persistent Synaptic Activity and Enhances the Signal-to-Noise Ratio in the Prefrontal Cortex
por: Kroener, Sven, et al.
Publicado: (2009)

Chronic Phencyclidine Increases Synapsin-1 and Synaptic Adaptation Proteins in the Medial Prefrontal Cortex
por: Pickering, Chris, et al.
Publicado: (2013)

Pathophysiology of Trans-Synaptic Adhesion Molecules: Implications for Epilepsy
por: Gorlewicz, Adam, et al.
Publicado: (2018)

Dopaminergic Suppression of Synaptic Transmission in the Lateral Entorhinal Cortex
por: Caruana, Douglas A., et al.
Publicado: (2008)

Differential synaptic mechanism underlying the neuronal modulation of prefrontal cortex, amygdala, and hippocampus in response to chronic postsurgical pain with or without cognitive deficits in rats
por: Li, Zhen, et al.
Publicado: (2022)

Distinct patterns of outcome valuation and amygdala-prefrontal cortex synaptic remodeling in adolescence and adulthood
por: Stolyarova, Alexandra, et al.
Publicado: (2015)

The prefrontal cortex /
por: Fuster, Joaquin M.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_8urcn7dmbtg4aqbjsjkaaq78mh