Cargando…
Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain V(H)H antibodies
The high binding affinities and specificities of antibodies have led to their use as drugs and biosensors. Single-domain V(H)H antibodies exhibit high specificity and affinity but have higher stability and solubility than conventional antibodies as they are single-domain proteins. In this work, base...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523659/ https://www.ncbi.nlm.nih.gov/pubmed/34663870 http://dx.doi.org/10.1038/s41598-021-98977-8 |