Cargando…
The Concept of α-Synuclein Strains and How Different Conformations May Explain Distinct Neurodegenerative Disorders
In the past few years, an increasing amount of studies primarily based on experimental models have investigated the existence of distinct α-synuclein strains and their different pathological effects. This novel concept could shed light on the heterogeneous nature of α-synucleinopathies, a group of d...
Autores principales: | Malfertheiner, Katja, Stefanova, Nadia, Heras-Garvin, Antonio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523670/ https://www.ncbi.nlm.nih.gov/pubmed/34675870 http://dx.doi.org/10.3389/fneur.2021.737195 |
Ejemplares similares
-
From Synaptic Protein to Prion: The Long and Controversial Journey of α-Synuclein
por: Heras-Garvin, Antonio, et al.
Publicado: (2020) -
α-Synuclein Strains: Does Amyloid Conformation Explain the Heterogeneity of Synucleinopathies?
por: Hoppe, Simon Oliver, et al.
Publicado: (2021) -
Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance
por: Lemos, Miguel, et al.
Publicado: (2020) -
Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy
por: Heras‐Garvin, Antonio, et al.
Publicado: (2018) -
High-salt diet does not boost neuroinflammation and neurodegeneration in a model of α-synucleinopathy
por: Heras-Garvin, Antonio, et al.
Publicado: (2020)