Cargando…

Multisystem inflammatory syndrome in adults: A case in a previously healthy adult

A 25‐year‐old previously healthy female presented to the emergency department (ED) with 5 days of rash, fevers, shortness of breath, and generalized weakness. She had presented to another ED 4 days previously and noted that her rash had improved, but her other symptoms were worsening. She had recove...

Descripción completa

Detalles Bibliográficos
Autores principales: Motzkus, Christine A, Whitaker, Nash, Lommel, Jennifer, Pettit, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523750/
https://www.ncbi.nlm.nih.gov/pubmed/34704088
http://dx.doi.org/10.1002/emp2.12426
_version_ 1784585356907118592
author Motzkus, Christine A
Whitaker, Nash
Lommel, Jennifer
Pettit, Nicholas
author_facet Motzkus, Christine A
Whitaker, Nash
Lommel, Jennifer
Pettit, Nicholas
author_sort Motzkus, Christine A
collection PubMed
description A 25‐year‐old previously healthy female presented to the emergency department (ED) with 5 days of rash, fevers, shortness of breath, and generalized weakness. She had presented to another ED 4 days previously and noted that her rash had improved, but her other symptoms were worsening. She had recovered from COVID‐19, confirmed by positive antigen test 5 weeks prior. On ED arrival, she was afebrile and persistently tachycardic to a rate of 120 beats per minute, despite aggressive fluid resuscitation with 3L of IV crystalloid. She was found to have a troponin elevated to 0.06 ng/mL in addition to a d‐dimer elevated to 1.42 mcg/mL FEU. She was admitted to the hospital where she developed hypotension requiring vasopressor support and was admitted to the intensive care unit (ICU). A transthoracic echocardiogram revealed a newly reduced ejection fraction of 31%. She was diagnosed with multisystem inflammatory syndrome in adults (MIS‐A). The patient received intravenous immunoglobulin and methylprednisolone 60 mg Q12 hours while admitted. She was discharged on hospital day 3 with a prednisone taper and is currently doing well at her most recent follow‐up with infectious disease.
format Online
Article
Text
id pubmed-8523750
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-85237502021-10-25 Multisystem inflammatory syndrome in adults: A case in a previously healthy adult Motzkus, Christine A Whitaker, Nash Lommel, Jennifer Pettit, Nicholas J Am Coll Emerg Physicians Open Infectious Disease A 25‐year‐old previously healthy female presented to the emergency department (ED) with 5 days of rash, fevers, shortness of breath, and generalized weakness. She had presented to another ED 4 days previously and noted that her rash had improved, but her other symptoms were worsening. She had recovered from COVID‐19, confirmed by positive antigen test 5 weeks prior. On ED arrival, she was afebrile and persistently tachycardic to a rate of 120 beats per minute, despite aggressive fluid resuscitation with 3L of IV crystalloid. She was found to have a troponin elevated to 0.06 ng/mL in addition to a d‐dimer elevated to 1.42 mcg/mL FEU. She was admitted to the hospital where she developed hypotension requiring vasopressor support and was admitted to the intensive care unit (ICU). A transthoracic echocardiogram revealed a newly reduced ejection fraction of 31%. She was diagnosed with multisystem inflammatory syndrome in adults (MIS‐A). The patient received intravenous immunoglobulin and methylprednisolone 60 mg Q12 hours while admitted. She was discharged on hospital day 3 with a prednisone taper and is currently doing well at her most recent follow‐up with infectious disease. John Wiley and Sons Inc. 2021-10-18 /pmc/articles/PMC8523750/ /pubmed/34704088 http://dx.doi.org/10.1002/emp2.12426 Text en © 2021 The Authors. JACEP Open published by Wiley Periodicals LLC on behalf of American College of Emergency Physicians https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Infectious Disease
Motzkus, Christine A
Whitaker, Nash
Lommel, Jennifer
Pettit, Nicholas
Multisystem inflammatory syndrome in adults: A case in a previously healthy adult
title Multisystem inflammatory syndrome in adults: A case in a previously healthy adult
title_full Multisystem inflammatory syndrome in adults: A case in a previously healthy adult
title_fullStr Multisystem inflammatory syndrome in adults: A case in a previously healthy adult
title_full_unstemmed Multisystem inflammatory syndrome in adults: A case in a previously healthy adult
title_short Multisystem inflammatory syndrome in adults: A case in a previously healthy adult
title_sort multisystem inflammatory syndrome in adults: a case in a previously healthy adult
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523750/
https://www.ncbi.nlm.nih.gov/pubmed/34704088
http://dx.doi.org/10.1002/emp2.12426
work_keys_str_mv AT motzkuschristinea multisysteminflammatorysyndromeinadultsacaseinapreviouslyhealthyadult
AT whitakernash multisysteminflammatorysyndromeinadultsacaseinapreviouslyhealthyadult
AT lommeljennifer multisysteminflammatorysyndromeinadultsacaseinapreviouslyhealthyadult
AT pettitnicholas multisysteminflammatorysyndromeinadultsacaseinapreviouslyhealthyadult