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Characterizing Intercellular Communication of Pan-Cancer Reveals SPP1+ Tumor-Associated Macrophage Expanded in Hypoxia and Promoting Cancer Malignancy Through Single-Cell RNA-Seq Data
Hypoxia is a characteristic of tumor microenvironment (TME) and is a major contributor to tumor progression. Yet, subtype identification of tumor-associated non-malignant cells at single-cell resolution and how they influence cancer progression under hypoxia TME remain largely unexplored. Here, we u...
Autores principales: | Wei, Jinfen, Chen, Zixi, Hu, Meiling, He, Ziqing, Jiang, Dawei, Long, Jie, Du, Hongli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523849/ https://www.ncbi.nlm.nih.gov/pubmed/34676217 http://dx.doi.org/10.3389/fcell.2021.749210 |
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