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Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report

BACKGROUND: Progressive renal insufficiency is frequent in heart failure patients with a left ventricular assist device (LVAD). The optimal strategy for long-term dialysis in LVAD patients and its effect on quality-of-life in these patients remain to be determined. CASE SUMMARY: Our 55-year-old pati...

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Autores principales: Koppel, Claire J, Jonker, Jacqueline T, Michels, Wieneke M, Beeres, Saskia L M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523880/
https://www.ncbi.nlm.nih.gov/pubmed/34671714
http://dx.doi.org/10.1093/ehjcr/ytab307
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author Koppel, Claire J
Jonker, Jacqueline T
Michels, Wieneke M
Beeres, Saskia L M A
author_facet Koppel, Claire J
Jonker, Jacqueline T
Michels, Wieneke M
Beeres, Saskia L M A
author_sort Koppel, Claire J
collection PubMed
description BACKGROUND: Progressive renal insufficiency is frequent in heart failure patients with a left ventricular assist device (LVAD). The optimal strategy for long-term dialysis in LVAD patients and its effect on quality-of-life in these patients remain to be determined. CASE SUMMARY: Our 55-year-old patient with pre-existing renal insufficiency received an LVAD as destination therapy because of advanced ischaemic heart failure. Six years after implantation, he developed end-stage renal disease for which peritoneal dialysis (PD) was initiated. Left ventricular assist device flow alterations during ultrafiltration did not cause clinical or technical problems. The patient’s exercise capacity increased and quality-of-life improved. Over 7.5 years after LVAD implantation and 16 months after PD initiation, he died from encephalitis. DISCUSSION: Despite initial improvement, renal function often gradually decreases after LVAD implantation. Data on long-term renal replacement therapy in LVAD patients are limited. Haemodialysis is most commonly applied. Conceptually, however, PD has advantages over haemodialysis including less bloodstream infections, less haemodynamic shifts, and the comfort of the ambulant setting. This case illustrates that PD in an LVAD patient is feasible and improves quality-of-life. Key factors contributing to successful PD in LVAD patients may be a good right ventricular function and close cardiology–nephrology collaboration.
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spelling pubmed-85238802021-10-19 Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report Koppel, Claire J Jonker, Jacqueline T Michels, Wieneke M Beeres, Saskia L M A Eur Heart J Case Rep Case Report BACKGROUND: Progressive renal insufficiency is frequent in heart failure patients with a left ventricular assist device (LVAD). The optimal strategy for long-term dialysis in LVAD patients and its effect on quality-of-life in these patients remain to be determined. CASE SUMMARY: Our 55-year-old patient with pre-existing renal insufficiency received an LVAD as destination therapy because of advanced ischaemic heart failure. Six years after implantation, he developed end-stage renal disease for which peritoneal dialysis (PD) was initiated. Left ventricular assist device flow alterations during ultrafiltration did not cause clinical or technical problems. The patient’s exercise capacity increased and quality-of-life improved. Over 7.5 years after LVAD implantation and 16 months after PD initiation, he died from encephalitis. DISCUSSION: Despite initial improvement, renal function often gradually decreases after LVAD implantation. Data on long-term renal replacement therapy in LVAD patients are limited. Haemodialysis is most commonly applied. Conceptually, however, PD has advantages over haemodialysis including less bloodstream infections, less haemodynamic shifts, and the comfort of the ambulant setting. This case illustrates that PD in an LVAD patient is feasible and improves quality-of-life. Key factors contributing to successful PD in LVAD patients may be a good right ventricular function and close cardiology–nephrology collaboration. Oxford University Press 2021-07-29 /pmc/articles/PMC8523880/ /pubmed/34671714 http://dx.doi.org/10.1093/ehjcr/ytab307 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Koppel, Claire J
Jonker, Jacqueline T
Michels, Wieneke M
Beeres, Saskia L M A
Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
title Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
title_full Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
title_fullStr Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
title_full_unstemmed Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
title_short Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
title_sort peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523880/
https://www.ncbi.nlm.nih.gov/pubmed/34671714
http://dx.doi.org/10.1093/ehjcr/ytab307
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