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Lactate in the tumour microenvironment: From immune modulation to therapy

Disordered metabolic states, which are characterised by hypoxia and elevated levels of metabolites, particularly lactate, contribute to the immunosuppression in the tumour microenvironment (TME). Excessive lactate secreted by metabolism-reprogrammed cancer cells regulates immune responses via causin...

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Detalles Bibliográficos
Autores principales:	Wang, Zi-Hao, Peng, Wen-Bei, Zhang, Pei, Yang, Xiang-Ping, Zhou, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524104/ https://www.ncbi.nlm.nih.gov/pubmed/34656878 http://dx.doi.org/10.1016/j.ebiom.2021.103627

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