RSV infection-elicited high MMP-12–producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration

Respiratory syncytial virus (RSV) infection often exacerbates bronchial asthma, but there is no licensed RSV vaccine or specific treatments. Here we show that RSV-induced alveolar macrophages, which produce high levels of matrix metalloproteinase-12 (MMP-12), exacerbate allergic airway inflammation...

Descripción completa

Detalles Bibliográficos
Autores principales: Makino, Airi, Shibata, Takehiko, Nagayasu, Mashiro, Hosoya, Ikuo, Nishimura, Toshiyo, Nakano, Chihiro, Nagata, Kisaburo, Ito, Toshihiro, Takahashi, Yoshimasa, Nakamura, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524145/
https://www.ncbi.nlm.nih.gov/pubmed/34703996
http://dx.doi.org/10.1016/j.isci.2021.103201

Ejemplares similares

Ejemplares similares