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Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease

Chronic kidney disease (CKD) is associated with substantial morbidity and mortality. We developed a mouse model that mimics human CKD with inflammation, extracellular matrix deposition, tubulointerstitial fibrosis, increased proteinuria, and associated reduction in glomerular filtration rate over ti...

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Detalles Bibliográficos
Autores principales:	Xin, Cuiyan, Lei, Jiahui, Wang, Qian, Yin, Yixia, Yang, Xiaoqian, Moran Guerrero, Jose Alberto, Sabbisetti, Venkata, Sun, Xiaoming, Vaidya, Vishal S., Bonventre, Joseph V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524153/ https://www.ncbi.nlm.nih.gov/pubmed/34703992 http://dx.doi.org/10.1016/j.isci.2021.103193

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