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Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer’s disease in nonhuman primates
As an insidious and slowly progressive neurodegenerative disorder, Alzheimer’s disease (AD) uniquely develops in humans but fails in other species. Therefore, it has been challenged to rebuild human AD in animals, including in non-human primates. Here, we bilaterally delivered synthetic Aβ oligomers...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524197/ https://www.ncbi.nlm.nih.gov/pubmed/34704001 http://dx.doi.org/10.1016/j.isci.2021.103207 |