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Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer’s disease in nonhuman primates

As an insidious and slowly progressive neurodegenerative disorder, Alzheimer’s disease (AD) uniquely develops in humans but fails in other species. Therefore, it has been challenged to rebuild human AD in animals, including in non-human primates. Here, we bilaterally delivered synthetic Aβ oligomers...

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Detalles Bibliográficos
Autores principales: Yue, Feng, Feng, Su, Lu, Chunling, Zhang, Ting, Tao, Guoxian, Liu, Jing, Yue, Chunmei, Jing, Naihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524197/
https://www.ncbi.nlm.nih.gov/pubmed/34704001
http://dx.doi.org/10.1016/j.isci.2021.103207