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Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis

Benzylisoquinoline alkaloids (BIAs) are a class of specialized metabolites with a diverse range of chemical structures and physiological effects. Codeine and morphine are two closely related BIAs with particularly useful analgesic properties. The aldo-keto reductase (AKR) codeinone reductase (COR) c...

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Detalles Bibliográficos
Autores principales:	Carr, Samuel C., Torres, Megan A., Morris, Jeremy S., Facchini, Peter J., Ng, Kenneth K.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524200/ https://www.ncbi.nlm.nih.gov/pubmed/34547292 http://dx.doi.org/10.1016/j.jbc.2021.101211

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