Cargando…

Silencing of MBD2 and EZH2 inhibits the proliferation of colorectal carcinoma cells by rescuing the expression of SFRP

The secreted frizzled related proteins (SFRPs) are extracellular inhibitors of WNT pathway signaling. Methyl-CpG binding domain protein 2 (MBD2) and enhancer of zeste homolog 2 (EZH2) are core members of the methylated DNA binding domain (MBD) and polycomb group (PcG) protein families for epigenetic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Yang, Wang, Feng, Yu, Jun, Zhang, Jing, Liu, Yuting, Li, Mengying, Qi, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524315/ https://www.ncbi.nlm.nih.gov/pubmed/34617573 http://dx.doi.org/10.3892/or.2021.8201

Ejemplares similares

EZH2 regulates sFRP4 expression without affecting the methylation of sFRP4 promoter DNA in colorectal cancer cell lines
por: Liu, Yuting, et al.
Publicado: (2020)

The Silencing of SFRP2 Expression in ESCC Is Due to Methylation of the Gene Promoter
por: Liu, Qian, et al.
Publicado: (2019)

Long noncoding RNA FALEC inhibits proliferation and metastasis of tongue squamous cell carcinoma by epigenetically silencing ECM1 through EZH2
por: Jia, Bo, et al.
Publicado: (2019)

Association between SFRP promoter hypermethylation and different types of cancer: A systematic review and meta-analysis
por: Yu, Jun, et al.
Publicado: (2019)

Expression of Sfrp2 Is Increased in Catagen of Hair Follicles and Inhibits Keratinocyte Proliferation
por: Kim, Bong-Kyu, et al.
Publicado: (2014)

MBD2 and MBD3: elusive functions and mechanisms
por: Menafra, Roberta, et al.
Publicado: (2014)

Expression of EZH2 in endometrial carcinoma and its effects on proliferation and invasion of endometrial carcinoma cells
por: Gu, Yuting, et al.
Publicado: (2017)

DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patients
por: Liu, Xinyan, et al.
Publicado: (2019)

Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of developing pollen
por: Ichino, Lucia, et al.
Publicado: (2022)

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer
por: Kodach, Liudmila L., et al.
Publicado: (2010)

Prognostic Relevance of SFRP1 Gene Promoter Methylation in Colorectal Carcinoma
por: Kumar, Alok, et al.
Publicado: (2019)

SFRP2 is a Novel Diagnostic Biomarker and Suppresses the Proliferation of Pituitary Adenoma
por: Huang, Rongxi, et al.
Publicado: (2022)

EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth
por: Bownes, Laura V., et al.
Publicado: (2021)

Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations
por: Bader, S, et al.
Publicado: (2000)

Myofibroblast-Derived SFRP1 as Potential Inhibitor of Colorectal Carcinoma Field Effect
por: Valcz, Gábor, et al.
Publicado: (2014)

Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2015)

DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells
por: Hainer, Sarah J, et al.
Publicado: (2016)

EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion
por: Yi, Xiaoqing, et al.
Publicado: (2017)

Silencing microRNA-27a inhibits proliferation and invasion of human osteosarcoma cells through the SFRP1-dependent Wnt/β-catenin signaling pathway
por: Mu, Yu, et al.
Publicado: (2019)

EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma
por: Xue, Liqiong, et al.
Publicado: (2019)

Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma
por: Sremac, Maja, et al.
Publicado: (2021)

Silencing homeobox C6 inhibits colorectal cancer cell proliferation
por: Ji, Meiling, et al.
Publicado: (2016)

Retracted: SFRP2 is a Novel Diagnostic Biomarker and Suppresses the Proliferation of Pituitary Adenoma
por: Journal of Oncology
Publicado: (2023)

MicroRNA-101-3p advances cisplatin sensitivity in bladder urothelial carcinoma through targeted silencing EZH2
por: Li, Bo, et al.
Publicado: (2019)

MiR-32 Inhibits Proliferation and Metastasis by Targeting EZH2 in Glioma
por: Zhang, Yuan, et al.
Publicado: (2019)

Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice
por: García-García, Patricia, et al.
Publicado: (2022)

Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer
por: Taniguchi, H, et al.
Publicado: (2012)

Effects of iodine-125 seeds on the methylation of SFRP(2) and P16 in colorectal cancer
por: LI, XIAOGANG, et al.
Publicado: (2013)

Study of SFRP1 and SFRP2 methylation status in patients with de novo Acute Myeloblastic Leukemia
por: Ghasemi, Ali, et al.
Publicado: (2015)

Targeted Disruption of the EZH2/EED Complex Inhibits EZH2-dependent Cancer
por: Kim, Woojin, et al.
Publicado: (2013)

EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy
por: Lui, Julian C., et al.
Publicado: (2016)

MON-532 Characterization of the Angiogenic Factor SFRP2 in Papillary Thyroid Carcinoma
por: Wofford, Wyatt O, et al.
Publicado: (2020)

High Stromal SFRP2 Expression in Urothelial Carcinoma Confers an Unfavorable Prognosis
por: Lai, Hong-Yue, et al.
Publicado: (2022)

Inverse Associations Between Circulating Secreted Frizzled Related Protein 2 (sFRP2) and Cardiometabolic Risk Factors
por: Cao, Mengying, et al.
Publicado: (2021)

LncRNA MSTO2P promotes colorectal cancer progression through epigenetically silencing CDKN1A mediated by EZH2
por: Guo, Mengjun, et al.
Publicado: (2022)

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
por: Günther, Katharina, et al.
Publicado: (2013)

Effects of silencing neuropilin-2 on proliferation, migration, and invasion of colorectal cancer HT-29
por: Zhan, Qi-Qi, et al.
Publicado: (2022)

SPRY4 suppresses proliferation and induces apoptosis of colorectal cancer cells by repressing oncogene EZH2
por: Guo, Jia, et al.
Publicado: (2021)

Curcumin inhibits the growth of triple‐negative breast cancer cells by silencing EZH2 and restoring DLC1 expression
por: Zhou, Xueliang, et al.
Publicado: (2020)

Impact of cinacalcet introduction on MBD management: the MBD-5D study in Japan
por: Fukuma, Shingo, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_e6gnvvecaa4r8saemdmja3vl2d