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The glycosylation status of MHC class I molecules impacts their interactions with TAPBPR

Glycosylation plays a crucial role in the folding, structure, quality control and trafficking of glycoproteins. Here, we explored whether the glycosylation status of MHC class I (MHC-I) molecules impacts their affinity for the peptide editor, TAPBPR. We demonstrate that the interaction between TAPBP...

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Detalles Bibliográficos
Autores principales: Ilca, F. Tudor, Boyle, Louise H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524320/
https://www.ncbi.nlm.nih.gov/pubmed/34543843
http://dx.doi.org/10.1016/j.molimm.2021.09.007