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Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome

BACKGROUND: Breast cancer (BC) progression to metastatic disease is the leading cause of death in women worldwide. Metastasis is driven by cancer stem cells (CSCs) and signals from their microenvironment. Interleukin (IL) 30 promotes BC progression, and its expression correlates with disease recurre...

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Detalles Bibliográficos
Autores principales:	Sorrentino, Carlo, Ciummo, Stefania Livia, D'Antonio, Luigi, Fieni, Cristiano, Lanuti, Paola, Turdo, Alice, Todaro, Matilde, Di Carlo, Emma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524378/ https://www.ncbi.nlm.nih.gov/pubmed/34663639 http://dx.doi.org/10.1136/jitc-2021-002966

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