(18)F-Fluorination: Challenge and Opportunity for Organic Chemists

[Image: see text] (18)F-fluorination is an important and growing field in organic synthesis that has attracted many chemists in the recent past. Here we present our own, biased perspective with a focus on our own chemistry that evaluates recent advances in the field and provides our opinion on the c...

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Autores principales: Halder, Riya, Ritter, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524428/
https://www.ncbi.nlm.nih.gov/pubmed/34428043
http://dx.doi.org/10.1021/acs.joc.1c01474
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author Halder, Riya
Ritter, Tobias
author_facet Halder, Riya
Ritter, Tobias
author_sort Halder, Riya
collection PubMed
description [Image: see text] (18)F-fluorination is an important and growing field in organic synthesis that has attracted many chemists in the recent past. Here we present our own, biased perspective with a focus on our own chemistry that evaluates recent advances in the field and provides our opinion on the challenges for the development of new chemistry, so that it may have an impact on imaging. We hope that the manuscript will provide a useful guide to chemists to develop reliable and robust reaction chemistry suitable for radiofluorination to have a real impact on human health.
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spelling pubmed-85244282021-10-19 (18)F-Fluorination: Challenge and Opportunity for Organic Chemists Halder, Riya Ritter, Tobias J Org Chem [Image: see text] (18)F-fluorination is an important and growing field in organic synthesis that has attracted many chemists in the recent past. Here we present our own, biased perspective with a focus on our own chemistry that evaluates recent advances in the field and provides our opinion on the challenges for the development of new chemistry, so that it may have an impact on imaging. We hope that the manuscript will provide a useful guide to chemists to develop reliable and robust reaction chemistry suitable for radiofluorination to have a real impact on human health. American Chemical Society 2021-08-24 2021-10-15 /pmc/articles/PMC8524428/ /pubmed/34428043 http://dx.doi.org/10.1021/acs.joc.1c01474 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Halder, Riya
Ritter, Tobias
(18)F-Fluorination: Challenge and Opportunity for Organic Chemists
title (18)F-Fluorination: Challenge and Opportunity for Organic Chemists
title_full (18)F-Fluorination: Challenge and Opportunity for Organic Chemists
title_fullStr (18)F-Fluorination: Challenge and Opportunity for Organic Chemists
title_full_unstemmed (18)F-Fluorination: Challenge and Opportunity for Organic Chemists
title_short (18)F-Fluorination: Challenge and Opportunity for Organic Chemists
title_sort (18)f-fluorination: challenge and opportunity for organic chemists
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524428/
https://www.ncbi.nlm.nih.gov/pubmed/34428043
http://dx.doi.org/10.1021/acs.joc.1c01474
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AT rittertobias 18ffluorinationchallengeandopportunityfororganicchemists

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