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A Review on Drug Delivery System for Tumor Therapy

In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, i...

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Autores principales: Liu, Guoxiang, Yang, Lina, Chen, Guang, Xu, Fenghua, Yang, Fanghao, Yu, Huaxin, Li, Lingne, Dong, Xiaolei, Han, Jingjing, Cao, Can, Qi, Jingyu, Su, Junzhe, Xu, Xiaohui, Li, Xiaoxia, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524443/
https://www.ncbi.nlm.nih.gov/pubmed/34675807
http://dx.doi.org/10.3389/fphar.2021.735446
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author Liu, Guoxiang
Yang, Lina
Chen, Guang
Xu, Fenghua
Yang, Fanghao
Yu, Huaxin
Li, Lingne
Dong, Xiaolei
Han, Jingjing
Cao, Can
Qi, Jingyu
Su, Junzhe
Xu, Xiaohui
Li, Xiaoxia
Li, Bing
author_facet Liu, Guoxiang
Yang, Lina
Chen, Guang
Xu, Fenghua
Yang, Fanghao
Yu, Huaxin
Li, Lingne
Dong, Xiaolei
Han, Jingjing
Cao, Can
Qi, Jingyu
Su, Junzhe
Xu, Xiaohui
Li, Xiaoxia
Li, Bing
author_sort Liu, Guoxiang
collection PubMed
description In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, including easy preparation, high efficiency, low toxicity, especially active tumor-targeting ability. Drug delivery systems are usually composed of delivery carriers, antitumor drugs, and even target molecules. At present, there are few comprehensive reports on a summary of drug delivery systems applied for tumor therapy. This review introduces the preparation, characteristics, and applications of several common delivery carriers and expounds the antitumor mechanism of different antitumor drugs in delivery carriers in detail which provides a more theoretical basis for clinical application of personalized cancer nanomedicine in the future.
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spelling pubmed-85244432021-10-20 A Review on Drug Delivery System for Tumor Therapy Liu, Guoxiang Yang, Lina Chen, Guang Xu, Fenghua Yang, Fanghao Yu, Huaxin Li, Lingne Dong, Xiaolei Han, Jingjing Cao, Can Qi, Jingyu Su, Junzhe Xu, Xiaohui Li, Xiaoxia Li, Bing Front Pharmacol Pharmacology In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, including easy preparation, high efficiency, low toxicity, especially active tumor-targeting ability. Drug delivery systems are usually composed of delivery carriers, antitumor drugs, and even target molecules. At present, there are few comprehensive reports on a summary of drug delivery systems applied for tumor therapy. This review introduces the preparation, characteristics, and applications of several common delivery carriers and expounds the antitumor mechanism of different antitumor drugs in delivery carriers in detail which provides a more theoretical basis for clinical application of personalized cancer nanomedicine in the future. Frontiers Media S.A. 2021-10-04 /pmc/articles/PMC8524443/ /pubmed/34675807 http://dx.doi.org/10.3389/fphar.2021.735446 Text en Copyright © 2021 Liu, Yang, Chen, Xu, Yang, Yu, Li, Dong, Han, Cao, Qi, Su, Xu, Li and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Liu, Guoxiang
Yang, Lina
Chen, Guang
Xu, Fenghua
Yang, Fanghao
Yu, Huaxin
Li, Lingne
Dong, Xiaolei
Han, Jingjing
Cao, Can
Qi, Jingyu
Su, Junzhe
Xu, Xiaohui
Li, Xiaoxia
Li, Bing
A Review on Drug Delivery System for Tumor Therapy
title A Review on Drug Delivery System for Tumor Therapy
title_full A Review on Drug Delivery System for Tumor Therapy
title_fullStr A Review on Drug Delivery System for Tumor Therapy
title_full_unstemmed A Review on Drug Delivery System for Tumor Therapy
title_short A Review on Drug Delivery System for Tumor Therapy
title_sort review on drug delivery system for tumor therapy
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524443/
https://www.ncbi.nlm.nih.gov/pubmed/34675807
http://dx.doi.org/10.3389/fphar.2021.735446
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