Cargando…
A Review on Drug Delivery System for Tumor Therapy
In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, i...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524443/ https://www.ncbi.nlm.nih.gov/pubmed/34675807 http://dx.doi.org/10.3389/fphar.2021.735446 |
_version_ | 1784585514353950720 |
---|---|
author | Liu, Guoxiang Yang, Lina Chen, Guang Xu, Fenghua Yang, Fanghao Yu, Huaxin Li, Lingne Dong, Xiaolei Han, Jingjing Cao, Can Qi, Jingyu Su, Junzhe Xu, Xiaohui Li, Xiaoxia Li, Bing |
author_facet | Liu, Guoxiang Yang, Lina Chen, Guang Xu, Fenghua Yang, Fanghao Yu, Huaxin Li, Lingne Dong, Xiaolei Han, Jingjing Cao, Can Qi, Jingyu Su, Junzhe Xu, Xiaohui Li, Xiaoxia Li, Bing |
author_sort | Liu, Guoxiang |
collection | PubMed |
description | In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, including easy preparation, high efficiency, low toxicity, especially active tumor-targeting ability. Drug delivery systems are usually composed of delivery carriers, antitumor drugs, and even target molecules. At present, there are few comprehensive reports on a summary of drug delivery systems applied for tumor therapy. This review introduces the preparation, characteristics, and applications of several common delivery carriers and expounds the antitumor mechanism of different antitumor drugs in delivery carriers in detail which provides a more theoretical basis for clinical application of personalized cancer nanomedicine in the future. |
format | Online Article Text |
id | pubmed-8524443 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85244432021-10-20 A Review on Drug Delivery System for Tumor Therapy Liu, Guoxiang Yang, Lina Chen, Guang Xu, Fenghua Yang, Fanghao Yu, Huaxin Li, Lingne Dong, Xiaolei Han, Jingjing Cao, Can Qi, Jingyu Su, Junzhe Xu, Xiaohui Li, Xiaoxia Li, Bing Front Pharmacol Pharmacology In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, including easy preparation, high efficiency, low toxicity, especially active tumor-targeting ability. Drug delivery systems are usually composed of delivery carriers, antitumor drugs, and even target molecules. At present, there are few comprehensive reports on a summary of drug delivery systems applied for tumor therapy. This review introduces the preparation, characteristics, and applications of several common delivery carriers and expounds the antitumor mechanism of different antitumor drugs in delivery carriers in detail which provides a more theoretical basis for clinical application of personalized cancer nanomedicine in the future. Frontiers Media S.A. 2021-10-04 /pmc/articles/PMC8524443/ /pubmed/34675807 http://dx.doi.org/10.3389/fphar.2021.735446 Text en Copyright © 2021 Liu, Yang, Chen, Xu, Yang, Yu, Li, Dong, Han, Cao, Qi, Su, Xu, Li and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Liu, Guoxiang Yang, Lina Chen, Guang Xu, Fenghua Yang, Fanghao Yu, Huaxin Li, Lingne Dong, Xiaolei Han, Jingjing Cao, Can Qi, Jingyu Su, Junzhe Xu, Xiaohui Li, Xiaoxia Li, Bing A Review on Drug Delivery System for Tumor Therapy |
title | A Review on Drug Delivery System for Tumor Therapy |
title_full | A Review on Drug Delivery System for Tumor Therapy |
title_fullStr | A Review on Drug Delivery System for Tumor Therapy |
title_full_unstemmed | A Review on Drug Delivery System for Tumor Therapy |
title_short | A Review on Drug Delivery System for Tumor Therapy |
title_sort | review on drug delivery system for tumor therapy |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524443/ https://www.ncbi.nlm.nih.gov/pubmed/34675807 http://dx.doi.org/10.3389/fphar.2021.735446 |
work_keys_str_mv | AT liuguoxiang areviewondrugdeliverysystemfortumortherapy AT yanglina areviewondrugdeliverysystemfortumortherapy AT chenguang areviewondrugdeliverysystemfortumortherapy AT xufenghua areviewondrugdeliverysystemfortumortherapy AT yangfanghao areviewondrugdeliverysystemfortumortherapy AT yuhuaxin areviewondrugdeliverysystemfortumortherapy AT lilingne areviewondrugdeliverysystemfortumortherapy AT dongxiaolei areviewondrugdeliverysystemfortumortherapy AT hanjingjing areviewondrugdeliverysystemfortumortherapy AT caocan areviewondrugdeliverysystemfortumortherapy AT qijingyu areviewondrugdeliverysystemfortumortherapy AT sujunzhe areviewondrugdeliverysystemfortumortherapy AT xuxiaohui areviewondrugdeliverysystemfortumortherapy AT lixiaoxia areviewondrugdeliverysystemfortumortherapy AT libing areviewondrugdeliverysystemfortumortherapy AT liuguoxiang reviewondrugdeliverysystemfortumortherapy AT yanglina reviewondrugdeliverysystemfortumortherapy AT chenguang reviewondrugdeliverysystemfortumortherapy AT xufenghua reviewondrugdeliverysystemfortumortherapy AT yangfanghao reviewondrugdeliverysystemfortumortherapy AT yuhuaxin reviewondrugdeliverysystemfortumortherapy AT lilingne reviewondrugdeliverysystemfortumortherapy AT dongxiaolei reviewondrugdeliverysystemfortumortherapy AT hanjingjing reviewondrugdeliverysystemfortumortherapy AT caocan reviewondrugdeliverysystemfortumortherapy AT qijingyu reviewondrugdeliverysystemfortumortherapy AT sujunzhe reviewondrugdeliverysystemfortumortherapy AT xuxiaohui reviewondrugdeliverysystemfortumortherapy AT lixiaoxia reviewondrugdeliverysystemfortumortherapy AT libing reviewondrugdeliverysystemfortumortherapy |