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Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells

ExoY is among the effectors that are injected by the type III secretion system (T3SS) of Pseudomonas aeruginosa into host cells. Inside eukaryotic cells, ExoY interacts with F-actin, which stimulates its potent nucleotidyl cyclase activity to produce cyclic nucleotide monophosphates (cNMPs). ExoY ha...

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Detalles Bibliográficos
Autores principales: Silistre, Hazel, Raoux-Barbot, Dorothée, Mancinelli, Federica, Sangouard, Flora, Dupin, Alice, Belyy, Alexander, Deruelle, Vincent, Renault, Louis, Ladant, Daniel, Touqui, Lhousseine, Mechold, Undine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524455/
https://www.ncbi.nlm.nih.gov/pubmed/34675890
http://dx.doi.org/10.3389/fmicb.2021.666097