Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3

Spinocerebellar ataxia 3 (SCA3, also known as Machado–Joseph disease) is a neurodegenerative disease caused by inheritance of a CAG repeat expansion within the ATXN3 gene, resulting in polyglutamine (polyQ) repeat expansion within the ataxin-3 protein. In this study, we have identified protein aggre...

Descripción completa

Detalles Bibliográficos
Autores principales: Robinson, Katherine J., Tym, Madelaine C., Hogan, Alison, Watchon, Maxinne, Yuan, Kristy C., Plenderleith, Stuart K., Don, Emily K., Laird, Angela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524651/
https://www.ncbi.nlm.nih.gov/pubmed/34473252
http://dx.doi.org/10.1242/dmm.049023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524651/
https://www.ncbi.nlm.nih.gov/pubmed/34473252
http://dx.doi.org/10.1242/dmm.049023

Ejemplares similares