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Multiple osteolytic primary peripheral T-cell bone lymphoma: the first case report

Peripheral T-cell lymphoma accounts for about 10% of all cases of non-Hodgkin’s lymphoma. However, less than 5% of patients with non-Hodgkin’s lymphoma present with hypercalcaemia as the initial symptom, and less than 1% present with primary bone lesions. We herein describe a 76-year-old Chinese man...

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Detalles Bibliográficos
Autores principales: Li, Chen, Wang, Weiguo, Xu, Lingyun, Zheng, Dingyun, Zhang, Miao, Zhang, Qin, Wu, Xiaoqian, Yao, Yue, Huang, Wenyue, Li, Xue, Ying, Peipei, Wang, Xiuxiu, Shang, Liu, Feng, Yuhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524712/
https://www.ncbi.nlm.nih.gov/pubmed/34657512
http://dx.doi.org/10.1177/03000605211052229
Descripción
Sumario:Peripheral T-cell lymphoma accounts for about 10% of all cases of non-Hodgkin’s lymphoma. However, less than 5% of patients with non-Hodgkin’s lymphoma present with hypercalcaemia as the initial symptom, and less than 1% present with primary bone lesions. We herein describe a 76-year-old Chinese man who was diagnosed with primary bone adult T-cell lymphoma with extensive osteolysis, including bone loss in the radius, as the initial manifestation. He had developed severe generalised bone pain and an inability to raise his arms. X-ray examination revealed osteolytic destruction of the forearm with loss of the radial diaphysis. The patient was diagnosed with peripheral T-cell lymphoma based on his immunohistochemical results. He began treatment with the CHOPE chemotherapy regimen, which resulted in significant improvement of his bone pain.