Profound inhibition of CD73-dependent formation of anti-inflammatory adenosine in B cells of SLE patients

BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that leads to a breakdown of tolerance to self-antigens resulting in inflammation and organ damage. The anti-inflammatory activity of CD73-derived adenosine is well documented, however, its role in SLE pathogenesis is unk...

Descripción completa

Detalles Bibliográficos
Autores principales: Hesse, Julia, Siekierka-Harreis, Magdalena, Steckel, Bodo, Alter, Christina, Schallehn, Merle, Honke, Nadine, Schnieringer, Marie-Laure, Wippich, Madita, Braband, Rebekka, Schneider, Matthias, Surowy, Harald, Wieczorek, Dagmar, Schrader, Jürgen, Pongratz, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524755/
https://www.ncbi.nlm.nih.gov/pubmed/34666225
http://dx.doi.org/10.1016/j.ebiom.2021.103616

Ejemplares similares

Ejemplares similares