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Mechano-inflammatory sensitivity of ACE2: Implications for the regional distribution of SARS-CoV-2 injury in the lung

The coronavirus disease (COVID-19) caused by SARS-CoV-2 can result in severe injury to the lung. Computed tomography images have revealed that the virus preferentially affects the base of the lung, which experiences larger tidal stretches than the apex. We hypothesize that the expression of both the...

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Detalles Bibliográficos
Autores principales: Bartolák-Suki, Erzsébet, Mondoñedo, Jarred R., Suki, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524802/
https://www.ncbi.nlm.nih.gov/pubmed/34678474
http://dx.doi.org/10.1016/j.resp.2021.103804