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Direct comparisons of efficacy and safety between actinomycin-D and methotrexate in women with low-risk gestational trophoblastic neoplasia: a meta-analysis of randomized and high-quality non-randomized studies

BACKGROUND: Actinomycin-D (Act-D) and Methotrexate (MTX) are both effective first-line agents for low-risk gestational trophoblastic neoplasia (LRGTN) with no consensus regarding which is more effective or less toxic. The primary objective of this meta-analysis is to compare Act-D with MTX in the tr...

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Detalles Bibliográficos
Autores principales: Hao, Jiatao, Zhou, Weihua, Zhang, Mengzhao, Yu, Hui, Zhang, Taohong, An, Ruifang, Xue, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524874/
https://www.ncbi.nlm.nih.gov/pubmed/34663255
http://dx.doi.org/10.1186/s12885-021-08849-7