Increase in the proportion of Plasmodium falciparum with kelch13 C580Y mutation and decline in pfcrt and pfmdr1 mutant alleles in Papua New Guinea

BACKGROUND: The C580Y mutation in the Plasmodium falciparum kelch13 gene is the most commonly observed variant in artemisinin-resistant isolates in the Greater Mekong Subregion (GMS). Until 2017, it had not been identified outside the GMS, except for Guyana/Amazonia. In 2017, three parasites carryin...

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Detalles Bibliográficos
Autores principales: Yoshida, Naoko, Yamauchi, Masato, Morikawa, Ryosuke, Hombhanje, Francis, Mita, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524940/
https://www.ncbi.nlm.nih.gov/pubmed/34666779
http://dx.doi.org/10.1186/s12936-021-03933-6

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