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Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study

BACKGROUND: The incidence of placenta preiva is rising. Cesarean delivery is identified as the only safe and appropriate mode of delivery for pregnancies with placenta previa. Anesthesia is important during the cesarean delivery. The aim of this study is to assess maternal and neonatal outcomes of p...

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Autores principales: Fan, Dazhi, Rao, Jiaming, Lin, Dongxin, Zhang, Huishan, Zhou, Zixing, Chen, Gengdong, Li, Pengsheng, Wang, Wen, Chen, Ting, Chen, Fengying, Ye, Yuping, Guo, Xiaoling, Liu, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524954/
https://www.ncbi.nlm.nih.gov/pubmed/34666687
http://dx.doi.org/10.1186/s12871-021-01472-w
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author Fan, Dazhi
Rao, Jiaming
Lin, Dongxin
Zhang, Huishan
Zhou, Zixing
Chen, Gengdong
Li, Pengsheng
Wang, Wen
Chen, Ting
Chen, Fengying
Ye, Yuping
Guo, Xiaoling
Liu, Zhengping
author_facet Fan, Dazhi
Rao, Jiaming
Lin, Dongxin
Zhang, Huishan
Zhou, Zixing
Chen, Gengdong
Li, Pengsheng
Wang, Wen
Chen, Ting
Chen, Fengying
Ye, Yuping
Guo, Xiaoling
Liu, Zhengping
author_sort Fan, Dazhi
collection PubMed
description BACKGROUND: The incidence of placenta preiva is rising. Cesarean delivery is identified as the only safe and appropriate mode of delivery for pregnancies with placenta previa. Anesthesia is important during the cesarean delivery. The aim of this study is to assess maternal and neonatal outcomes of patients with placenta previa managed with neuraxial anesthesia as compared to those who underwent general anesthesia during cesarean delivery. METHODS: A retrospective cohort study was performed of all patients with placenta preiva at our large academic institution from January 1, 2014 to June 30, 2019. Patients were managed neuraxial anesthesia and general anesthesia during cesarean delivery. RESULTS: We identified 1234 patients with placenta previa who underwent cesarean delivery at our institution. Neuraxial anesthesia was performed in 737 (59.7%), and general anesthesia was completed in 497 (40.3%) patients. The mean estimated blood loss at neuraxial anesthesia of 558.96 ± 42.77 ml were significantly lower than the estimated blood loss at general anesthesia of 1952.51 ± 180 ml (p < 0.001). One hundred and forty-six of 737 (19.8%) patients required blood transfusion at neuraxial anesthesia, whereas 381 out of 497 (76.7%) patients required blood transfusion at general anesthesia. The rate neonatal asphyxia and admission to NICU at neuraxial anesthesia was significantly lower than general anesthesia (2.7% vs. 19.5 and 18.2% vs. 44.1%, respectively). After adjusting confounding factors, blood loss was less, Apgar score at 1- and 5-min were higher, and the rate of blood transfusion, neonatal asphyxia, and admission to NICU were lower in the neuraxial group. CONCLUSIONS: Our data demonstrated that neuraxial anesthesia is associated with better maternal and neonatal outcomes during cesarean delivery in women with placenta previa. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12871-021-01472-w.
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spelling pubmed-85249542021-10-22 Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study Fan, Dazhi Rao, Jiaming Lin, Dongxin Zhang, Huishan Zhou, Zixing Chen, Gengdong Li, Pengsheng Wang, Wen Chen, Ting Chen, Fengying Ye, Yuping Guo, Xiaoling Liu, Zhengping BMC Anesthesiol Research BACKGROUND: The incidence of placenta preiva is rising. Cesarean delivery is identified as the only safe and appropriate mode of delivery for pregnancies with placenta previa. Anesthesia is important during the cesarean delivery. The aim of this study is to assess maternal and neonatal outcomes of patients with placenta previa managed with neuraxial anesthesia as compared to those who underwent general anesthesia during cesarean delivery. METHODS: A retrospective cohort study was performed of all patients with placenta preiva at our large academic institution from January 1, 2014 to June 30, 2019. Patients were managed neuraxial anesthesia and general anesthesia during cesarean delivery. RESULTS: We identified 1234 patients with placenta previa who underwent cesarean delivery at our institution. Neuraxial anesthesia was performed in 737 (59.7%), and general anesthesia was completed in 497 (40.3%) patients. The mean estimated blood loss at neuraxial anesthesia of 558.96 ± 42.77 ml were significantly lower than the estimated blood loss at general anesthesia of 1952.51 ± 180 ml (p < 0.001). One hundred and forty-six of 737 (19.8%) patients required blood transfusion at neuraxial anesthesia, whereas 381 out of 497 (76.7%) patients required blood transfusion at general anesthesia. The rate neonatal asphyxia and admission to NICU at neuraxial anesthesia was significantly lower than general anesthesia (2.7% vs. 19.5 and 18.2% vs. 44.1%, respectively). After adjusting confounding factors, blood loss was less, Apgar score at 1- and 5-min were higher, and the rate of blood transfusion, neonatal asphyxia, and admission to NICU were lower in the neuraxial group. CONCLUSIONS: Our data demonstrated that neuraxial anesthesia is associated with better maternal and neonatal outcomes during cesarean delivery in women with placenta previa. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12871-021-01472-w. BioMed Central 2021-10-19 /pmc/articles/PMC8524954/ /pubmed/34666687 http://dx.doi.org/10.1186/s12871-021-01472-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Fan, Dazhi
Rao, Jiaming
Lin, Dongxin
Zhang, Huishan
Zhou, Zixing
Chen, Gengdong
Li, Pengsheng
Wang, Wen
Chen, Ting
Chen, Fengying
Ye, Yuping
Guo, Xiaoling
Liu, Zhengping
Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
title Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
title_full Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
title_fullStr Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
title_full_unstemmed Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
title_short Anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
title_sort anesthetic management in cesarean delivery of women with placenta previa: a retrospective cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524954/
https://www.ncbi.nlm.nih.gov/pubmed/34666687
http://dx.doi.org/10.1186/s12871-021-01472-w
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