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Encouraging long‐term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high‐risk patients with resectable pancreatic carcinoma

INTRODUCTION: Preoperative autophagy inhibition with hydroxychloroquine (HCQ) in combination with gemcitabine in pancreatic adenocarcinoma (PDAC) has been shown to be safe and effective in inducing a serum biomarker response and increase resection rates in a previous phase I/II clinical trial. We ai...

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Detalles Bibliográficos
Autores principales: AlMasri, Samer S., Zenati, Mazen S., Desilva, Annissa, Nassour, Ibrahim, Boone, Brian A., Singhi, Aatur D., Bartlett, David L., Liotta, Lance A., Espina, Virginia, Loughran, Patricia, Lotze, Michael T., Paniccia, Alessandro, Zeh, Herbert J., Zureikat, Amer H., Bahary, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525088/
https://www.ncbi.nlm.nih.gov/pubmed/34559451
http://dx.doi.org/10.1002/cam4.4211