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Encouraging long‐term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high‐risk patients with resectable pancreatic carcinoma
INTRODUCTION: Preoperative autophagy inhibition with hydroxychloroquine (HCQ) in combination with gemcitabine in pancreatic adenocarcinoma (PDAC) has been shown to be safe and effective in inducing a serum biomarker response and increase resection rates in a previous phase I/II clinical trial. We ai...
Autores principales: | AlMasri, Samer S., Zenati, Mazen S., Desilva, Annissa, Nassour, Ibrahim, Boone, Brian A., Singhi, Aatur D., Bartlett, David L., Liotta, Lance A., Espina, Virginia, Loughran, Patricia, Lotze, Michael T., Paniccia, Alessandro, Zeh, Herbert J., Zureikat, Amer H., Bahary, Nathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525088/ https://www.ncbi.nlm.nih.gov/pubmed/34559451 http://dx.doi.org/10.1002/cam4.4211 |
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