Cargando…

Driver gene alterations profiling of Chinese non‐small cell lung cancer and the effects of co‐occurring alterations on immunotherapy

BACKGROUND: Molecular testing for alterations in oncogenic driver genes and targeted therapies have become standard procedures for non‐small cell lung cancer (NSCLC) patients. However, little evidence has shed light on the pattern of co‐existence of driver genes in NSCLC, and whether they may have d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Shengjie, Du, Wenjuan, Sun, Qiong, Zhao, Xiao, Qin, Boyu, Shi, Duozhi, Wan, Chong, Wu, Zhiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525092/ https://www.ncbi.nlm.nih.gov/pubmed/34599863 http://dx.doi.org/10.1002/cam4.4178

Ejemplares similares

The expression of small RNAs in exosomes of follicular fluid altered in human polycystic ovarian syndrome
por: Hu, Junhe, et al.
Publicado: (2020)

Alteration of the gut microbiota associated with childhood obesity by 16S rRNA gene sequencing
por: Chen, Xiaowei, et al.
Publicado: (2020)

Altered gut microbiota associated with symptom severity in schizophrenia
por: Li, Shijia, et al.
Publicado: (2020)

Intestinal parasitic infection alters bacterial gut microbiota in children
por: Toro-Londono, Miguel A., et al.
Publicado: (2019)

Serum metabolome alterations in patients with early nonalcoholic fatty liver disease
por: Wang, Xuemei, et al.
Publicado: (2022)

A set of novel SNP loci for differentiating continental populations and three Chinese populations
por: Jin, Xiao-Ye, et al.
Publicado: (2019)

Ginsenoside Rb1 enhanced immunity and altered the gut microflora in mice immunized by H1N1 influenza vaccine
por: Wan, Chuanqi, et al.
Publicado: (2023)

Comparative proteogenomics profiling of non-small and small lung carcinoma cell lines using mass spectrometry
por: Wu, Jingyu, et al.
Publicado: (2020)

Identification of key genes in non-small cell lung cancer by bioinformatics analysis
por: Zhang, Li, et al.
Publicado: (2019)

Using bioinformatics and metabolomics to identify altered granulosa cells in patients with diminished ovarian reserve
por: He, Ruifen, et al.
Publicado: (2020)

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules
por: Nersisyan, Stepan, et al.
Publicado: (2022)

Transcriptomic heterogeneity of driver gene mutations reveals novel mutual exclusivity and improves exploration of functional associations
por: Lan, Yujia, et al.
Publicado: (2021)

Cancer driver genes: a guilty by resemblance doctrine
por: Ramsahai, Emilie, et al.
Publicado: (2019)

Alien vs. predator: bacterial challenge alters coral microbiomes unless controlled by Halobacteriovorax predators
por: Welsh, Rory M., et al.
Publicado: (2017)

Whole genome sequencing analysis identifies recurrent structural alterations in esophageal squamous cell carcinoma
por: Dutta, Munmee, et al.
Publicado: (2020)

Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma
por: Tessiri, Supharada, et al.
Publicado: (2022)

The use of gene interaction networks to improve the identification of cancer driver genes
por: Ramsahai, Emilie, et al.
Publicado: (2017)

Long noncoding RNAs to predict postoperative recurrence in bladder cancer and to develop a new molecular classification system
por: Li, Zhiyong, et al.
Publicado: (2021)

Co-occurring genomic alterations and immunotherapy efficacy in NSCLC
por: Zhang, Fan, et al.
Publicado: (2022)

Integrative analysis of common genes and driver mutations implicated in hormone stimulation for four cancers in women
por: Bhyan, Salma Begum, et al.
Publicado: (2019)

Evolutionary analysis of vision genes identifies potential drivers of visual differences between giraffe and okapi
por: Ishengoma, Edson, et al.
Publicado: (2017)

Feeding bovine milks with low or high IgA levels is associated with altered re-establishment of murine intestinal microbiota after antibiotic treatment
por: Hodgkinson, Alison J., et al.
Publicado: (2016)

Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/ choroid in chick model of form-deprivation myopia
por: Giummarra, Loretta, et al.
Publicado: (2018)

Novel Driver Strength Index highlights important cancer genes in TCGA PanCanAtlas patients
por: Belikov, Aleksey V., et al.
Publicado: (2022)

Plasma miRNA profiles associated with stable warfarin dosage in Chinese patients
por: Zhao, Li, et al.
Publicado: (2020)

Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?
por: Smith, Thomas C.A., et al.
Publicado: (2016)

An RNA-sequencing-based transcriptome for a significantly prognostic novel driver signature identification in bladder urothelial carcinoma
por: Liu, Danqi, et al.
Publicado: (2020)

Temporal and spatial differences in the vaginal microbiome of Chinese healthy women
por: Du, Limin, et al.
Publicado: (2023)

Identification and validation of a genomic mutation signature as a predictor for immunotherapy in NSCLC
por: Wang, Zemin, et al.
Publicado: (2022)

Impact of mini-driver genes in the prognosis and tumor features of colorectal cancer samples: a novel perspective to support current biomarkers
por: Campos Segura, Anthony Vladimir, et al.
Publicado: (2023)

High mutations in fatty acid metabolism contribute to a better prognosis of small‐cell lung cancer patients treated with chemotherapy
por: Lyu, Qiong, et al.
Publicado: (2021)

Autophagy-related genes prognosis signature as potential predictive markers for immunotherapy in hepatocellular carcinoma
por: Mao, Deli, et al.
Publicado: (2020)

Identification and validation of a novel signature for prediction the prognosis and immunotherapy benefit in bladder cancer
por: Zhang, Yichi, et al.
Publicado: (2022)

Autophagy-related prognostic signature for survival prediction of triple negative breast cancer
por: Yang, Qiong, et al.
Publicado: (2022)

Integrating multi-type aberrations from DNA and RNA through dynamic mapping gene space for subtype-specific breast cancer driver discovery
por: Xi, Jianing, et al.
Publicado: (2023)

Immune activity score to assess the prognosis, immunotherapy and chemotherapy response in gastric cancer and experimental validation
por: Wu, Xuan, et al.
Publicado: (2023)

Immunotherapy in Non-Small-Cell Lung Cancer Patients with Driver Alterations: A New Strategy?
por: Krzyżanowska, Natalia, et al.
Publicado: (2022)

Nomogram to predict the prognosis of parotid gland mucoepidermoid carcinoma: a population-based study of 1306 cases
por: Sun, Jian, et al.
Publicado: (2019)

Integration of exome-seq and mRNA-seq using DawnRank, identified genes involved in innate immunity as drivers of breast cancer in the Indian cohort
por: Nirgude, Snehal, et al.
Publicado: (2023)

Reproducible combinatorial regulatory networks elucidate novel oncogenic microRNAs in non-small cell lung cancer
por: Mitra, Ramkrishna, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5kl2ugoa90mpn4l2712gitu9j3