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Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study

BACKGROUND: Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. METHODS: A total...

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Autores principales: Xing, Ling‐Xiao, Zhang, Jing, Shen, Hui, Tang, Xiao‐Lu, He, Lu, Wu, Jia‐Zhu, Li, Jian‐Yong, Miao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525132/
https://www.ncbi.nlm.nih.gov/pubmed/34480528
http://dx.doi.org/10.1002/cam4.4232
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author Xing, Ling‐Xiao
Zhang, Jing
Shen, Hui
Tang, Xiao‐Lu
He, Lu
Wu, Jia‐Zhu
Li, Jian‐Yong
Miao, Yi
author_facet Xing, Ling‐Xiao
Zhang, Jing
Shen, Hui
Tang, Xiao‐Lu
He, Lu
Wu, Jia‐Zhu
Li, Jian‐Yong
Miao, Yi
author_sort Xing, Ling‐Xiao
collection PubMed
description BACKGROUND: Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. METHODS: A total of 3375 eligible cases diagnosed from 2004 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Association of marital status with stage and survival in patients with MF was analyzed. RESULTS: Married patients were more likely to be diagnosed at T1 stage (p = 0.041). And married patients were less likely to present with lymph node involvement (p = 0.007). More favorable overall survival (p < 0.001) and cancer‐specific survival (p < 0.001) were demonstrated in married patients as compared with divorced patients or widowed patients. A clinically feasible prognostic model including marital status, age, sex, race, and stage at presentation was constructed. CONCLUSION: Married marital status was associated with earlier stage at diagnosis and longer survival compared with divorced or widowed marital status in patients with MF.
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spelling pubmed-85251322021-10-26 Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study Xing, Ling‐Xiao Zhang, Jing Shen, Hui Tang, Xiao‐Lu He, Lu Wu, Jia‐Zhu Li, Jian‐Yong Miao, Yi Cancer Med Cancer Prevention BACKGROUND: Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. METHODS: A total of 3375 eligible cases diagnosed from 2004 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Association of marital status with stage and survival in patients with MF was analyzed. RESULTS: Married patients were more likely to be diagnosed at T1 stage (p = 0.041). And married patients were less likely to present with lymph node involvement (p = 0.007). More favorable overall survival (p < 0.001) and cancer‐specific survival (p < 0.001) were demonstrated in married patients as compared with divorced patients or widowed patients. A clinically feasible prognostic model including marital status, age, sex, race, and stage at presentation was constructed. CONCLUSION: Married marital status was associated with earlier stage at diagnosis and longer survival compared with divorced or widowed marital status in patients with MF. John Wiley and Sons Inc. 2021-09-04 /pmc/articles/PMC8525132/ /pubmed/34480528 http://dx.doi.org/10.1002/cam4.4232 Text en © 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Prevention
Xing, Ling‐Xiao
Zhang, Jing
Shen, Hui
Tang, Xiao‐Lu
He, Lu
Wu, Jia‐Zhu
Li, Jian‐Yong
Miao, Yi
Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
title Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
title_full Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
title_fullStr Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
title_full_unstemmed Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
title_short Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
title_sort association of marital status with stage and survival in patients with mycosis fungoides: a population‐based study
topic Cancer Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525132/
https://www.ncbi.nlm.nih.gov/pubmed/34480528
http://dx.doi.org/10.1002/cam4.4232
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