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Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review

Pseudomyxoma peritonei (PMP) is a rare and uncommon condition, characterized by the presence of mucinous ascites in the abdominal cavity. The most common cause of PMP is mucinous adenocarcinoma of the appendix, followed by neoplasms of the ovary, endocervix, fallopian tube, alimentary organs, urachu...

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Autores principales: Kostov, Stoyan, Kornovski, Yavor, Slavchev, Stanislav, Ivanova, Yonka, Dzhenkov, Deyan, Yordanov, Angel, Slavcheva, Svetoslava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525259/
https://www.ncbi.nlm.nih.gov/pubmed/34703416
http://dx.doi.org/10.5114/pm.2021.109120
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author Kostov, Stoyan
Kornovski, Yavor
Slavchev, Stanislav
Ivanova, Yonka
Dzhenkov, Deyan
Yordanov, Angel
Slavcheva, Svetoslava
author_facet Kostov, Stoyan
Kornovski, Yavor
Slavchev, Stanislav
Ivanova, Yonka
Dzhenkov, Deyan
Yordanov, Angel
Slavcheva, Svetoslava
author_sort Kostov, Stoyan
collection PubMed
description Pseudomyxoma peritonei (PMP) is a rare and uncommon condition, characterized by the presence of mucinous ascites in the abdominal cavity. The most common cause of PMP is mucinous adenocarcinoma of the appendix, followed by neoplasms of the ovary, endocervix, fallopian tube, alimentary organs, urachus, urinary bladder, lung, mucinous cyst of the spleen, and breast. Herein, we report a case of a 64-year-old postmenopausal woman (gravida 2, para 2) who presented at the department of gynecology with a short history of nausea and abdominal distention. Abdominal and vaginal ultrasonography showed a large amount of free fluid in the pelvis with hyperechoic echogenicity and right pelvic tumor with mixed echogenicity. Computed tomography demonstrated the presence of a heterogeneous, hypodense mass, without contrast enhancement, located on the right side of the pelvis, near the right ovary. Laparotomy was performed. Revision of the abdominal cavity revealed a large amount of yellow gelatinous mucinous ascites – approximately 1.5 l. A tumor (6 x 7 cm in diameter), arising from the appendix and located in the pouch of Douglas near the right ovary, was observed. Histopathology examination revealed poorly differentiated mucinous appendiceal adenocarcinoma, comprising up to 50% signet ring cells. Gastrointestinal tumors such as appendiceal neoplasms combined with PMP may mimic ovarian carcinomas. Computed tomography, abdominal/vaginal ultrasonography and tumor marker levels (carcino-embryonic antigen, carbohydrate antigen 19.9, carbohydrate antigen Ca-125) may establish the diagnosis. A differential diagnosis with appendiceal tumors should be considered for patients with right pelvic masses.
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spelling pubmed-85252592021-10-25 Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review Kostov, Stoyan Kornovski, Yavor Slavchev, Stanislav Ivanova, Yonka Dzhenkov, Deyan Yordanov, Angel Slavcheva, Svetoslava Prz Menopauzalny Case Report Pseudomyxoma peritonei (PMP) is a rare and uncommon condition, characterized by the presence of mucinous ascites in the abdominal cavity. The most common cause of PMP is mucinous adenocarcinoma of the appendix, followed by neoplasms of the ovary, endocervix, fallopian tube, alimentary organs, urachus, urinary bladder, lung, mucinous cyst of the spleen, and breast. Herein, we report a case of a 64-year-old postmenopausal woman (gravida 2, para 2) who presented at the department of gynecology with a short history of nausea and abdominal distention. Abdominal and vaginal ultrasonography showed a large amount of free fluid in the pelvis with hyperechoic echogenicity and right pelvic tumor with mixed echogenicity. Computed tomography demonstrated the presence of a heterogeneous, hypodense mass, without contrast enhancement, located on the right side of the pelvis, near the right ovary. Laparotomy was performed. Revision of the abdominal cavity revealed a large amount of yellow gelatinous mucinous ascites – approximately 1.5 l. A tumor (6 x 7 cm in diameter), arising from the appendix and located in the pouch of Douglas near the right ovary, was observed. Histopathology examination revealed poorly differentiated mucinous appendiceal adenocarcinoma, comprising up to 50% signet ring cells. Gastrointestinal tumors such as appendiceal neoplasms combined with PMP may mimic ovarian carcinomas. Computed tomography, abdominal/vaginal ultrasonography and tumor marker levels (carcino-embryonic antigen, carbohydrate antigen 19.9, carbohydrate antigen Ca-125) may establish the diagnosis. A differential diagnosis with appendiceal tumors should be considered for patients with right pelvic masses. Termedia Publishing House 2021-09-13 2021-09 /pmc/articles/PMC8525259/ /pubmed/34703416 http://dx.doi.org/10.5114/pm.2021.109120 Text en Copyright © 2021 Termedia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) )
spellingShingle Case Report
Kostov, Stoyan
Kornovski, Yavor
Slavchev, Stanislav
Ivanova, Yonka
Dzhenkov, Deyan
Yordanov, Angel
Slavcheva, Svetoslava
Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
title Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
title_full Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
title_fullStr Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
title_full_unstemmed Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
title_short Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
title_sort pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer – a case report with literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525259/
https://www.ncbi.nlm.nih.gov/pubmed/34703416
http://dx.doi.org/10.5114/pm.2021.109120
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