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Case Report: Sustained Remission Due to PD-1-Inhibition in a Metastatic Melanoma Patient With Depleted B Cells

INTRODUCTION: Checkpoint-Inhibition (CPI) with PD-1- and PD-L1-inhibitors is a well-established therapy for advanced stage melanoma patients. CPI mainly acts via T-lymphocytes. However, recent literature suggests also a role for B cells modulating its efficacy and tolerability of CPI. CASE REPORT: W...

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Detalles Bibliográficos
Autores principales:	Wulfken, Lena Margarethe, Becker, Jürgen Christian, Hayajneh, Rami, Wagner, Annette Doris, Schaper-Gerhardt, Katrin, Flatt, Nina, Grimmelmann, Imke, Gutzmer, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525286/ https://www.ncbi.nlm.nih.gov/pubmed/34675925 http://dx.doi.org/10.3389/fimmu.2021.733961

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