Oral Immunization With a Plant HSP90-SAG1 Fusion Protein Produced in Tobacco Elicits Strong Immune Responses and Reduces Cyst Number and Clinical Signs of Toxoplasmosis in Mice

Plant 90kDa heat shock protein (HSP90) is a potent adjuvant that increases both humoral and cellular immune responses to diverse proteins and peptides. In this study, we explored whether Arabidopsis thaliana HSP90 (AtHsp81.2) can improve the immune effects of a Toxoplasma gondii surface antigen 1 (S...

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Detalles Bibliográficos
Autores principales: Sánchez-López, Edwin F., Corigliano, Mariana G., Oliferuk, Sonia, Ramos-Duarte, Victor A., Rivera, Maximiliano, Mendoza-Morales, Luisa F., Angel, Sergio O., Sander, Valeria A., Clemente, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525317/
https://www.ncbi.nlm.nih.gov/pubmed/34675949
http://dx.doi.org/10.3389/fpls.2021.726910

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