On the Selectivity of Heparan Sulfate Recognition by SARS-CoV-2 Spike Glycoprotein

[Image: see text] SARS-CoV-2 infects human cells through its surface spike glycoprotein (SgP), which relies on host cell surface heparan sulfate (HS) proteoglycans that facilitate interaction with the ACE2 receptor. Targeting this process could lead to inhibitors of early steps in viral entry. Scree...

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Detalles Bibliográficos
Autores principales: Chittum, John E., Sankaranarayanan, Nehru Viji, O’Hara, Connor P., Desai, Umesh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525342/
https://www.ncbi.nlm.nih.gov/pubmed/34786180
http://dx.doi.org/10.1021/acsmedchemlett.1c00343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525342/
https://www.ncbi.nlm.nih.gov/pubmed/34786180
http://dx.doi.org/10.1021/acsmedchemlett.1c00343

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