Genomic Engineering in Human Hematopoietic Stem Cells: Hype or Hope?

Many gene editing techniques are developed and tested, yet, most of these are optimized for transformed cell lines, which differ from their primary cell counterparts in terms of transfectability, cell death propensity, differentiation capability, and chromatin accessibility to gene editing tools. Re...

Descripción completa

Detalles Bibliográficos
Autores principales: Klaver-Flores, Stefanie, Zittersteijn, Hidde A., Canté-Barrett, Kirsten, Lankester, Arjan, Hoeben, Rob C., Gonçalves, Manuel A. F. V., Pike-Overzet, Karin, Staal, Frank J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525357/
https://www.ncbi.nlm.nih.gov/pubmed/34713237
http://dx.doi.org/10.3389/fgeed.2020.615619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525357/
https://www.ncbi.nlm.nih.gov/pubmed/34713237
http://dx.doi.org/10.3389/fgeed.2020.615619

Ejemplares similares