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Gene Editing and Genotoxicity: Targeting the Off-Targets

Gene editing technologies show great promise for application to human disease as a result of rapid developments in targeting tools notably based on ZFN, TALEN, and CRISPR-Cas systems. Precise modification of a DNA sequence is now possible in mature human somatic cells including stem and progenitor c...

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Detalles Bibliográficos
Autores principales:	Blattner, Georges, Cavazza, Alessia, Thrasher, Adrian J., Turchiano, Giandomenico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genome Editing
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525370/ https://www.ncbi.nlm.nih.gov/pubmed/34713236 http://dx.doi.org/10.3389/fgeed.2020.613252

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