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An Improved CRISPR/dCas9 Interference Tool for Neuronal Gene Suppression

The expression of genetic material governs brain development, differentiation, and function, and targeted manipulation of gene expression is required to understand contributions of gene function to health and disease states. Although recent improvements in CRISPR/dCas9 interference (CRISPRi) technol...

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Detalles Bibliográficos
Autores principales:	Duke, Corey G., Bach, Svitlana V., Revanna, Jasmin S., Sultan, Faraz A., Southern, Nicholas T., Davis, M. Natalie, Carullo, Nancy V. N., Bauman, Allison J., Phillips, Robert A., Day, Jeremy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genome Editing
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525373/ https://www.ncbi.nlm.nih.gov/pubmed/34713218 http://dx.doi.org/10.3389/fgeed.2020.00009

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