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Normal Iron Homeostasis Requires the Transporter SLC48A1 for Efficient Heme-Iron Recycling in Mammals

In mammals over 65% of the total body iron is located within erythrocytes in the heme moieties of hemoglobin. Iron homeostasis requires iron absorbed from the diet by the gut as well as recycling of iron after the destruction of senescent erythrocytes. Senescent erythrocytes are engulfed by reticulo...

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Detalles Bibliográficos
Autores principales: Simmons, William R., Wain, Lily, Toker, Joseph, Jagadeesh, Jaya, Garrett, Lisa J., Pek, Rini H., Hamza, Iqbal, Bodine, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525403/
https://www.ncbi.nlm.nih.gov/pubmed/34713217
http://dx.doi.org/10.3389/fgeed.2020.00008

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