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Normal Iron Homeostasis Requires the Transporter SLC48A1 for Efficient Heme-Iron Recycling in Mammals
In mammals over 65% of the total body iron is located within erythrocytes in the heme moieties of hemoglobin. Iron homeostasis requires iron absorbed from the diet by the gut as well as recycling of iron after the destruction of senescent erythrocytes. Senescent erythrocytes are engulfed by reticulo...
Autores principales: | Simmons, William R., Wain, Lily, Toker, Joseph, Jagadeesh, Jaya, Garrett, Lisa J., Pek, Rini H., Hamza, Iqbal, Bodine, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525403/ https://www.ncbi.nlm.nih.gov/pubmed/34713217 http://dx.doi.org/10.3389/fgeed.2020.00008 |
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