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Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies

Therapeutic advances for neurological disorders are challenging due to limited accessibility of the human central nervous system and incomplete understanding of disease mechanisms. Many neurological diseases lack precision treatments, leading to significant disease burden and poor outcome for affect...

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Detalles Bibliográficos
Autores principales: McTague, Amy, Rossignoli, Giada, Ferrini, Arianna, Barral, Serena, Kurian, Manju A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525405/
https://www.ncbi.nlm.nih.gov/pubmed/34713254
http://dx.doi.org/10.3389/fgeed.2021.630600