Mercaptopurine-Loaded Sandwiched Tri-Layered Composed of Electrospun Polycaprolactone/Poly(Methyl Methacrylate) Nanofibrous Scaffolds as Anticancer Carrier with Antimicrobial and Antibiotic Features: Sandwich Configuration Nanofibers, Release Study and in vitro Bioevaluation Tests

BACKGROUND: 6-Mercaptopurine (6-MP) is a potential anti-cancer agent which its therapeutic and limitation applicability due to its high toxicity. OBJECTIVE: Herein, 6-MP was loaded into tri-layered sandwich nanofibrous scaffold (the top layer composed of poly methyl methacrylate/polycaprolactone (PM...

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Detalles Bibliográficos
Autores principales: Salim, Samar A, Kamoun, Elbadawy A, Evans, Stephen, EL-Moslamy, Shahira H, El-Fakharany, Esmail M, Elmazar, Mohamed M, Abdel-Aziz, A F, Abou-Saleh, R H, Salaheldin, Taher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525416/
https://www.ncbi.nlm.nih.gov/pubmed/34703223
http://dx.doi.org/10.2147/IJN.S332920

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