Acquisition of the L452R Mutation in the ACE2-Binding Interface of Spike Protein Triggers Recent Massive Expansion of SARS-CoV-2 Variants

We report that there is a recent global expansion of numerous independent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with mutation L452R in the receptor-binding domain (RBD) of the spike protein. The massive emergence of L452R variants was first linked to lineage B.1.427/B...

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Detalles Bibliográficos
Autores principales: Tchesnokova, Veronika, Kulasekara, Hemantha, Larson, Lydia, Bowers, Victoria, Rechkina, Elena, Kisiela, Dagmara, Sledneva, Yulia, Choudhury, Debarati, Maslova, Iryna, Deng, Kai, Kutumbaka, Kirthi, Geng, Hao, Fowler, Curtis, Greene, Dina, Ralston, James, Samadpour, Mansour, Sokurenko, Evgeni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525575/
https://www.ncbi.nlm.nih.gov/pubmed/34379531
http://dx.doi.org/10.1128/JCM.00921-21

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